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KMID : 0363219920300040524
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Korean Journal of Dermatology
1992 Volume.30 No. 4 p.524 ~ p.528
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A Case of Griseofulvin-induced Phototoxic Reaction
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Abstract
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We report a case of phototoxic reaction in a 48-year-old female induced by griseofulvin ingestion. The patient had erythematous papules, vesicles and patches on the sun-exposed aresas. Phototest revealed a decreased minimal erythemal dose to UVA
(10J/㎠). Photopatch tests with 1%, 5%, 10% Griseofulvin ointment and vaseline as a control and photoingestion tests with Griseofulvin (50mg b. i. d.) were all negative. After the cessation of Griseofulvin(r), her skin lesions were markedly
improved
with complete loss of photosensitivity. (Kor J Dermatol 1992;30(4):524-528)
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